B cell primary immune responses
نویسندگان
چکیده
منابع مشابه
CD21/CD19 coreceptor signaling promotes B cell survival during primary immune responses.
The adaptive immune response is tightly regulated to limit responding cells in an Ag-specific manner. On B cells, coreceptors CD21/CD19 modulate the strength of BCR signals, potentially influencing cell fate. The importance of the CD95 pathway was examined in response of B cells to moderate affinity Ag using an adoptive transfer model of lysozyme-specific Ig transgenic (HEL immunoglobulin trans...
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Rho family GTPases regulate diverse cellular events, such as cell motility, polarity, and vesicle traffic. Although a wealth of data exists on the canonical Rho GTPases RhoA, Rac1, and Cdc42, several other family members remain poorly studied. In B cells, we recently demonstrated a critical role for Cdc42 in plasma cell differentiation. In this study, we focus on a close homolog of Cdc42, TC10 ...
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ژورنال
عنوان ژورنال: Immunological Reviews
سال: 2019
ISSN: 0105-2896,1600-065X
DOI: 10.1111/imr.12756